Others
have symptoms beginning after an incubation period of 1-3
weeks.
Symptoms are high fever, vomiting, diarrhea, cough, pains
and generalized weakness. Inflammation of eyes, throat, face
and neck may occur.
After
3-6 days bleeding occurs.
Survivors
may be left with hair loss, deafness, and loss of coordination.
Diagnosis
is initially difficult to differentiate.
White
patches are present on the tousle.
A
blood test helps confirm cases. IV treatment, with anti-viral
helps.
Since
there may be some time before people exhibit symptoms a strong
suspicion should be kept in returning travelers with high
fever, who have been to endemic areas, no matter how short
their stay.
Lassa
fever is an arena virus and is transmitted to people by contact
with infected rat urine and also by person -to- person contact.
It can cause severe illness including bleeding and meningo-encephalitis
with lack of effective therapy, but the vast majority of people
infected exhibit minimal symptoms
Risk
to travelers is very small but exists for health care workers.
Usually infected people will exhibit symptoms within 21 days
of return.
Differential diagnosis includes other viruses caught from
mosquitoes or other insects (Dengue fever, Yellow fever, O'nyong-nyong,
Chikungunya, Rift valley fever, Crimean-Congo fever and Hanta
fevers.
Lassa Fever links:
WHO http://www.who.int/mediacentre/factsheets/fs179/en/
travelhealth.co.uh http://www.travelhealth.co.uk/diseases/lassa.htm
TKH Virology: http://www.tarakharper.com/v_lassa.htm
CDC site: http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/lassaf.htm
CDC slide set: http://www.cdc.gov/ncidod/dvrd/spb/mnpages/lassaslides.htm
Adoption.com
http://library.adoption.com/Health-Issues/Lassa-Fever/article/1319/1.html
eurosurveillance.org
http://www.eurosurveillance.org/em/v07n03/0703-226.asp
ncib
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12534129&dopt=Abstract
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